Reproduction Abstracts

The composition of the external environment can have a significant impact on intracellular signaling pathways during early embryonic development. Components of the culture media, especially amino acids, are known to improve embryo development. We have shown that L-proline and L-glutamine improve development to the blastocyst stage by acting in a growth factor-like way. The aim of this study is to investigate the effect of amino acids on signaling pathways in the...

The inclusion of amino acids in pre-implantation embryo culture media is known to improve the rate of development and embryo viability. Our studies have shown that embryos cultured in L-proline from the zygote to the blastocyst stage develop better than embryos cultured in the absence of amino acids. This study aimed to identify the pre-implantation stage(s) at which L-proline transport is required for development to be improved and then to charac...